Triglycerides

Triglycerides are blood fats measured to help assess heart and pancreatitis risk; nonfasting testing is often acceptable [1][4].

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Test Summary

Sample Type 
Blood
Required Blood
Analysis Type
Serum; enzymatic colorimetric
Collection method
In person at the lab; at-home where available

Why test

Triglycerides

?

- Screen as part of a lipid panel to estimate cardiovascular risk and risk‑enhancing factors [1][3] - Evaluate very high levels that may increase pancreatitis risk [2][4] - Monitor response to lifestyle changes or treatments that target triglycerides [1][4] - Help investigate possible secondary causes of high triglycerides (e.g., diabetes, hypothyroidism, medications) [2]

What is

Triglycerides

?

- Screen as part of a lipid panel to estimate cardiovascular risk and risk‑enhancing factors [1][3] - Evaluate very high levels that may increase pancreatitis risk [2][4] - Monitor response to lifestyle changes or treatments that target triglycerides [1][4] - Help investigate possible secondary causes of high triglycerides (e.g., diabetes, hypothyroidism, medications) [2]

What insights will i get from

Triglycerides

?

- Nonfasting samples are acceptable for routine screening; repeat fasting if nonfasting triglycerides ≥400 mg/dL [1] - Persistent fasting triglycerides ≥175 mg/dL may support higher ASCVD risk discussions [1] - Very high levels (≥500 mg/dL) signal pancreatitis risk; risk is greater when ≥1000 mg/dL [2][4] - Repeat testing can confirm unexpected results and prompt search for secondary causes [2]

Sample type & collection

- Blood sample from a vein; measured as part of a lipid panel [1][3] - Fasting: It depends. Nonfasting is acceptable; fasting preferred for high results or diagnosis [1][2] - Recent food or alcohol can transiently raise triglycerides; follow pretest instructions [3][5] - If nonfasting triglycerides ≥400 mg/dL, a fasting recheck is advised [1]

Triglycerides

is best interpreted with:

- Full lipid panel: total cholesterol, HDL‑C, LDL‑C, non‑HDL‑C [1][3] - Apolipoprotein B or non‑HDL‑C may better reflect atherogenic particle burden [1][4] - Glucose or A1C to evaluate metabolic health and diabetes context [2][5]

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Triglycerides

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Limits & interferences with

Triglycerides

:

- Meals and recent alcohol can elevate triglycerides temporarily [2][3][5] - Pregnancy and some medications can raise triglycerides [2][5] - Uncontrolled diabetes, hypothyroidism, kidney or liver disease can increase levels [2] - Calculated LDL‑C is unreliable when triglycerides are high; consider direct LDL‑C or alternatives [1]

Sources:

[1] AHA/ACC. 2018 Guideline on the Management of Blood Cholesterol. (2019). https://www.ahajournals.org/doi/10.1161/CIR.0000000000000625 [2] Endocrine Society. Evaluation and Treatment of Hypertriglyceridemia Guideline. (2012). https://academic.oup.com/jcem/article/97/9/2969/2536648 [3] MedlinePlus. Triglycerides Test. (2024). https://medlineplus.gov/lab-tests/triglycerides-test/ [4] ACC. 2021 Expert Consensus Decision Pathway: ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia. (2021). https://www.jacc.org/doi/10.1016/j.jacc.2021.06.011 [5] NIH NHLBI. High Blood Triglycerides. (2022). https://www.nhlbi.nih.gov/health/high-blood-triglycerides
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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