HDL Cholesterol

HDL cholesterol helps carry cholesterol away from arteries and offers insight into heart health.

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HDL Cholesterol
 test

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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

HDL Cholesterol

?

  • Helps estimate heart risk with other factors.
  • Part of a standard lipid panel.
  • Tracks lifestyle changes like exercise and diet.
  • Useful when triglycerides or weight change.
  • Informs prevention planning with your clinician.

What is

HDL Cholesterol

?

  • Helps estimate heart risk with other factors.
  • Part of a standard lipid panel.
  • Tracks lifestyle changes like exercise and diet.
  • Useful when triglycerides or weight change.
  • Informs prevention planning with your clinician.

What insights will i get from

HDL Cholesterol

?

  • Low: Linked with higher heart disease risk.
  • High: May reflect healthier lifestyle or genetics.
  • Very high: Not always protective; interpret with other lipids.
  • Trends: Improving HDL alongside lower LDL is encouraging.
  • Not a target: Raising HDL alone has not lowered risk in trials.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Morning preferred; consistent timing helps
  • Collection: In person at the lab; at-home where available
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Avoid heavy alcohol and intense exercise 24 hours before
  • Turnaround: 1–3 business days

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HDL Cholesterol

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HDL Cholesterol
 test

Limits & interferences with

HDL Cholesterol

:

  • Strenuous exercise within 24 hours may raise HDL.
  • Smoking can lower HDL.
  • Heavy alcohol intake may raise HDL.
  • Weight changes can shift HDL.
  • Special situations: Pregnancy or illness—confirm when recovered.

Questions about

HDL Cholesterol

:

  • Do I need to fast? No. Fasting isn’t required for HDL alone. Your clinician may ask for fasting with a full lipid panel or very high triglycerides.
  • Can HDL be too high? Very high HDL isn’t always protective. Interpret it with LDL, triglycerides, and apolipoprotein B.
  • How can I improve HDL? Move regularly, stop smoking, choose healthy fats, and keep a healthy weight. These habits support heart health.
  • How often should I test? Usually with routine checkups. Test sooner if your risk or care plan changes.

Sources:

  • American College of Cardiology/American Heart Association — 2018 Guideline on the Management of Blood Cholesterol. (2018). https://www.ahajournals.org/doi/10.1161/CIR.0000000000000625
  • CDC — HDL Cholesterol: The “Good” Cholesterol. (2023). https://www.cdc.gov/cholesterol/hdl-cholesterol.htm
  • NIH MedlinePlus — HDL Cholesterol Test. (2024). https://medlineplus.gov/lab-tests/hdl-cholesterol-high-density-lipoprotein/
  • ARUP Consult — Lipid Panel. (2022). https://arupconsult.com/content/lipid-panel
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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