Lipoprotein (a)

An inherited cholesterol-carrying particle that helps refine your lifetime heart and stroke risk.

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Lipoprotein (a)
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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Lipoprotein (a)

?

Doctors order lipoprotein(a) to refine your risk for heart disease, stroke, or aortic valve disease, especially with family history or early events. It can shed light on high cholesterol that doesn’t respond as expected and helps decide how intensively to manage LDL cholesterol and other risks. Because levels are mostly genetic and stable, many people only need a one-time test. You can test this marker with Aniva across Germany and Finland.

What is

Lipoprotein (a)

?

Doctors order lipoprotein(a) to refine your risk for heart disease, stroke, or aortic valve disease, especially with family history or early events. It can shed light on high cholesterol that doesn’t respond as expected and helps decide how intensively to manage LDL cholesterol and other risks. Because levels are mostly genetic and stable, many people only need a one-time test. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Lipoprotein (a)

?

High: Linked with higher long-term risk of heart attack, stroke, peripheral artery disease, and aortic valve narrowing. This may prompt closer attention to LDL cholesterol, apolipoprotein B, and overall risk reduction. Family members may benefit from a one-time test.
Low: Generally reassuring and not linked to added cardiovascular risk. Keep up heart-healthy habits and monitor standard lipids as advised. Because levels change little over time, repeat testing is uncommon unless a different method is used or after major new therapy.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Any time when well; avoid testing during acute illness or pregnancy.
  • Collection: Venipuncture into serum separator tube.
  • Typical volume: 1 mL
  • Analysis: Serum immunoassay; isoform-insensitive method preferred.
  • Prep tips: Stay hydrated; avoid strenuous exercise on the day.
  • Turnaround: 2-5 business days

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Lipoprotein (a)

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Lipoprotein (a)
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Limits & interferences with

Lipoprotein (a)

:

Common factors that can skew results include acute infection or inflammation, pregnancy, and recent surgery. Estrogen therapy, niacin, and PCSK9 inhibitors can lower measured values; assay differences and isoform sensitivity may also shift results. Intense endurance exercise, dehydration, and sample mishandling can cause minor variability. Fasting is not required.

Special situations: consider repeating when recovered from illness, at least 3 months postpartum, or after starting new lipid-lowering therapy, using the same lab method when possible.

Questions about

Lipoprotein (a)

:

What does a high result mean? It signals extra inherited risk for heart and stroke. Your clinician will interpret it alongside cholesterol, apolipoprotein B, blood pressure, and lifestyle.

Do I need to fast for this test? No. Fasting is not required for lipoprotein(a).

What can affect my result? Levels are mostly genetic and stable. Pregnancy, acute illness, certain hormones, some medicines, and assay differences can shift results slightly.

How often should I test? Many people need a one-time test. Recheck if the lab method changes or after major new therapy, as advised by your clinician.

How long do results take? Most labs report results in 2-5 business days.

What should I discuss with my clinician? How the result changes your overall risk plan, targets for LDL cholesterol and apolipoprotein B, lifestyle steps, and whether family members should be tested.

Sources:

  • European Atherosclerosis Society — Lipoprotein(a) as a cardiovascular risk factor: consensus statement. (2022). https://academic.oup.com/eurheartj/article/43/39/3925/6670982
  • ACC/AHA — 2018 Guideline on the Management of Blood Cholesterol. (2019). https://www.ahajournals.org/doi/10.1161/CIR.0000000000000625
  • National Lipid Association — Scientific Statement on Lipoprotein(a). (2019). https://www.lipid.org/sites/default/files/files/NLA_Lp(a)_Scientific_Statement(1).pdf
  • MedlinePlus — Lipoprotein (a) Blood Test. (2024). https://medlineplus.gov/lab-tests/lipoprotein-a-blood-test/
  • ARUP Consult — Lipoprotein(a). (2023). https://arupconsult.com/ati/lipoprotein-a-lpa
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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