Bilirubin / Albumin Ratio

This ratio compares bilirubin to albumin, offering context for jaundice and overall liver balance.

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Bilirubin / Albumin Ratio
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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Bilirubin / Albumin Ratio

?

Clinicians may order this ratio when bilirubin is high or albumin is low to add context to jaundice and liver reserve. It can help guide follow-up with other liver tests, imaging, or a medication review. In newborn care, some teams consider it alongside bilirubin charts to assess risk. You can test this marker with Aniva across Germany and Finland.

What is

Bilirubin / Albumin Ratio

?

Clinicians may order this ratio when bilirubin is high or albumin is low to add context to jaundice and liver reserve. It can help guide follow-up with other liver tests, imaging, or a medication review. In newborn care, some teams consider it alongside bilirubin charts to assess risk. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Bilirubin / Albumin Ratio

?

High: May reflect more bilirubin or less albumin binding, which can occur with bile flow issues, liver stress, faster red blood cell breakdown, or malnutrition. Consider checking direct bilirubin and liver enzymes, and review medicines and alcohol.
Low: Usually not concerning; often reflects a healthy balance with lower bilirubin or higher albumin. Track trends and interpret with other liver tests. This ratio is not guideline-endorsed; no standardized cutoffs.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Morning draw preferred
  • Collection: Serum tube; protect sample from light
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Stay hydrated; avoid heavy exercise 24 hours before; share all medicines and supplements
  • Turnaround: 1–3 business days

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Bilirubin / Albumin Ratio

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Bilirubin / Albumin Ratio
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Limits & interferences with

Bilirubin / Albumin Ratio

:

Common factors include dehydration, recent hard exercise, and acute illness, which can shift albumin levels. Some medicines (for example, rifampin, probenecid, and certain HIV drugs like atazanavir) can raise bilirubin without liver damage. High-dose vitamin C can falsely lower bilirubin in some assays. Prolonged tourniquet time or a hemolyzed sample can distort results, and bilirubin is light-sensitive, so samples should be protected from bright light.

Special situations include pregnancy, severe inflammation, or newborn testing; confirm unexpected results with a repeat sample and clinician review.

Questions about

Bilirubin / Albumin Ratio

:

What does a high result mean? It suggests more bilirubin compared with albumin. This can occur with bile flow problems, liver stress, or low albumin; discuss next steps with your clinician.

Do I need to fast for this test? No. Fasting is not required for the bilirubin/albumin ratio.

What can affect the result? Some medicines (like rifampin or atazanavir), high-dose vitamin C, dehydration, recent hard exercise, and sample handling can shift results.

How often should I check it? Testing is usually done when there are symptoms, abnormal liver tests, or for follow-up. Your clinician may repeat it to track trends.

How quickly will I get results? Most labs report results in about 1–3 business days.

What should I discuss with my clinician? Share all medicines and supplements, alcohol use, and any symptoms such as yellow skin, dark urine, pale stools, or fatigue.

Sources:

  • MedlinePlus — Bilirubin blood test. (2023). https://medlineplus.gov/lab-tests/bilirubin-blood-test/
  • MedlinePlus — Albumin blood test. (2023). https://medlineplus.gov/lab-tests/albumin-blood-test/
  • AASLD — Evaluation of abnormal liver chemistries. (2017). https://www.aasld.org/practice-guidelines/evaluation-abnormal-liver-chemistries
  • ARUP Consult — Liver disease evaluation. (2024). https://arupconsult.com/content/liver-disease-evaluation
  • American Academy of Pediatrics — Management of hyperbilirubinemia in the newborn infant. (2022). https://publications.aap.org/pediatrics/article/150/3/e2022058859/188925/
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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