Total bilirubin shows how well your liver clears bilirubin, a yellow pigment from red blood cells.
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Clinicians order total bilirubin to check liver and bile duct health, investigate yellowing of the skin or eyes, or dark urine. It also helps monitor known liver conditions and medicines that may affect the liver. Results often guide next steps, like fractionated (direct/indirect) bilirubin or a full liver panel. You can test this marker with Aniva across Germany and Finland.
Clinicians order total bilirubin to check liver and bile duct health, investigate yellowing of the skin or eyes, or dark urine. It also helps monitor known liver conditions and medicines that may affect the liver. Results often guide next steps, like fractionated (direct/indirect) bilirubin or a full liver panel. You can test this marker with Aniva across Germany and Finland.
High: May suggest liver stress, slowed bile flow, increased red blood cell breakdown, or a common inherited pattern (Gilbert syndrome). Levels can rise with fasting, illness, or certain medicines. Consider repeat testing and checking direct bilirubin and liver enzymes. A simple step is to avoid alcohol and review medicines with your clinician.
Low: Usually not meaningful and needs no action.
Common factors include fasting or very low-calorie diets, dehydration, strenuous exercise, recent illness, alcohol, and pregnancy. Drugs like rifampin, atazanavir, indinavir, probenecid, and some antibiotics can raise levels; high-dose vitamin C may falsely lower them. Hemolysis in the tube and exposure of the sample to light can skew results; taking the sample at a consistent time helps with trends.
Special situations include pregnancy, newborn testing, and known Gilbert syndrome—confirm with repeat or fractionated bilirubin and discuss context with your clinician.
What does a high total bilirubin mean? It often means the liver is not clearing bilirubin well, bile flow is slowed, or red blood cell breakdown is increased.
Do medications or supplements affect results? Yes. Some antibiotics, HIV medicines, and rifampin can raise it. High-dose vitamin C may falsely lower it.
Do I need to fast for this test? No. Fasting is not required, though very strict fasting can temporarily raise levels.
How often should I test? As advised by your clinician. It’s often checked with a liver panel for symptoms or when monitoring medicines or known liver disease.
How long do results take? Most labs report results within 1–3 business days.
What should I discuss with my clinician? Share symptoms, medication and supplement use, alcohol intake, recent illnesses, and any history of Gilbert syndrome.
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