Vitamin B12

A simple blood test for the vitamin that supports red blood cells, energy, and nerve health.

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Vitamin B12
 test

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Test Summary

Sample Type 
Blood
Required Blood
1 mL
Analysis Type
Serum
Collection method
In person at the lab; at-home where available

Why test

Vitamin B12

?

Clinicians order vitamin B12 testing to look for causes of tiredness, tingling or numbness, memory changes, or certain types of anemia. It also helps check people with vegan diets, gut conditions or surgery, and those taking medicines like metformin or acid-reducing drugs. Results can guide follow-up tests (such as methylmalonic acid or folate) and inform nutrition plans. You can test this marker with Aniva across Germany and Finland.

What is

Vitamin B12

?

Clinicians order vitamin B12 testing to look for causes of tiredness, tingling or numbness, memory changes, or certain types of anemia. It also helps check people with vegan diets, gut conditions or surgery, and those taking medicines like metformin or acid-reducing drugs. Results can guide follow-up tests (such as methylmalonic acid or folate) and inform nutrition plans. You can test this marker with Aniva across Germany and Finland.

What insights will i get from

Vitamin B12

?

High: Often from supplements or recent injections; sometimes seen with other conditions. Consider retesting after pausing nonessential supplements and review medicines.
Low: May reflect low intake or poor absorption and can affect blood and nerve health. Discuss diet, medicines, and follow‑ups like methylmalonic acid or homocysteine to confirm. If you take B12, try testing before your usual dose.

Sample type & collection

  • Sample: Blood
  • Fasting: No
  • Best timing: Any time of day
  • Collection: In person at the lab; at-home where available
  • Typical volume: 1 mL
  • Analysis: Serum
  • Prep tips: Avoid high‑dose biotin for 24–72 hours if safe; list supplements and medicines
  • Turnaround: 1–3 business days

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Vitamin B12

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Vitamin B12
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Limits & interferences with

Vitamin B12

:

Common factors that can skew results include recent B12 shots or high‑dose supplements, multivitamins, and high‑dose biotin. Timing your test right before your usual supplement dose can reduce short‑term spikes. Medicines that reduce stomach acid and metformin may lower B12 over time. Pregnancy, acute illness, recent transfusion, and sample issues (like severe hemolysis) can also affect results.

Special situations (when to confirm or adjust): borderline results, symptoms despite a normal value, pregnancy, older age, or testing soon after injections—consider methylmalonic acid or homocysteine, and discuss timing and supplements with your clinician.

Questions about

Vitamin B12

:

What do my Vitamin B12 results mean? A low result suggests limited intake or absorption. A high result often reflects supplements or recent injections; discuss next steps with your clinician.

Do I need to fast for this test? No. You can test any time of day unless your clinician gives different instructions.

What can affect my Vitamin B12 result? High‑dose biotin, recent B12 shots or large supplements, and testing soon after a dose can raise levels. Acid‑reducing medicines and metformin may lower B12 over time.

How often should I test Vitamin B12? If you are at risk or on treatment, retest every 3–12 months as advised. Otherwise, repeat only if symptoms or risk factors change.

How fast will I get results? Most labs report results in 1–3 business days.

What should I discuss with my clinician? Share symptoms, diet (including vegan or low‑animal foods), and all supplements and medicines. Ask whether folate, methylmalonic acid, or homocysteine testing is helpful.

Sources:

  • NIH Office of Dietary Supplements — Vitamin B12 Fact Sheet for Health Professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
  • MedlinePlus — Vitamin B12 Level. (2024). https://medlineplus.gov/lab-tests/vitamin-b12-level/
  • ARUP Consult — Cobalamin (Vitamin B12) and Folate Deficiency. (2023). https://arupconsult.com/content/cobalamin-vitamin-b12-and-folate-deficiency
  • NICE CKS — Anaemia - B12 and folate deficiency. (2023). https://cks.nice.org.uk/topics/anaemia-b12-and-folate-deficiency/
  • NHS — Vitamin B12 or folate deficiency anaemia. (2023). https://www.nhs.uk/conditions/vitamin-b12-or-folate-deficiency-anaemia/
Medical disclaimer: This content is for informational purposes only and is not medical advice. Always discuss results with a qualified healthcare professional.

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