Globulin is a group of blood proteins that reflect immune activity and overall protein balance.
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Clinicians order globulin to assess protein balance, immune activity, and liver or kidney function. It helps evaluate inflammation, chronic infections, and nutrition. Abnormal results often lead to checks of albumin, total protein, liver enzymes, or protein electrophoresis. You can test this marker with Aniva across Germany and Finland.
Clinicians order globulin to assess protein balance, immune activity, and liver or kidney function. It helps evaluate inflammation, chronic infections, and nutrition. Abnormal results often lead to checks of albumin, total protein, liver enzymes, or protein electrophoresis. You can test this marker with Aniva across Germany and Finland.
High: Often reflects increased antibodies from ongoing inflammation or infection; dehydration can also raise levels. Sometimes linked to a single abnormal protein band, which may prompt protein electrophoresis.
Low: May suggest protein loss (kidney or gut), reduced production in liver problems, poor nutrition, or overhydration. This marker is not guideline-endorsed; no standardized cutoffs. Review trends with albumin and total protein, and consider hydration and medications before retesting.
Common factors that may skew results include dehydration or overhydration, recent IV fluids, prolonged tourniquet time, pregnancy, strenuous exercise, and recent infection or vaccination. Estrogen therapy, steroids, and androgens can shift protein levels; IV immunoglobulin and recent transfusion can raise globulin. Try to test when well and consistently hydrated.
Special situations (when to confirm or adjust): repeat when not acutely ill, consider timing after transfusion or IVIG, and interpret carefully during pregnancy or kidney/liver flare-ups.
What does a high or low globulin mean? High often reflects immune activity or dehydration. Low can suggest protein loss, reduced production, or overhydration. Trends guide context.
Do I need to fast for this test? No. Fasting is not required for a standard globulin measurement.
What can affect my result? Hydration, recent illness, exercise, IV fluids, hormones, steroids, and IVIG can change values. Consistent timing helps when tracking trends.
How often should I test globulin? Most people test only when a clinician is evaluating symptoms or monitoring a condition. If results change, your clinician may recheck in weeks to months.
How long do results take? Most labs report results within 1–3 working days.
What should I discuss with my clinician? Review hydration, medicines, and supplements. Ask whether to check albumin, total protein, or do protein electrophoresis for clarity.
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